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Nitroprusside does not have a hypotension effect only


Nitroprusside does not have a hypotension effect only

المعلومة

Nitroprusside does not have a hypotension effect only, it also inhibits platelets aggregation but how hot sauce?
contact with RBCs leads to decomposition of the drug and release nitric oxide.
Nitric oxide is one of the platelets aggreation inhibitors.
Other inhibitors are: PGI2 and fibrin splits

المرجع

Kaplan Pharmacology and Pharmcard

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