تصفح
دخول
تسجيل
نسيتها؟

Acute Cutaneous Lupus Erythematosus


Acute Cutaneous Lupus Erythematosus

Acute Cutaneous Lupus Erythematosus

This 18 year old SLE patient came to our Department due to a recent onset (3 months earlier) of malar rash and constitutional symptoms (weakness and malaise). The patient reported having a 5-year history of Raynaud's phenomenon and arthralgia.
Abnormal results of laboratory studies included the presence of ANA, anti-nDNA, anti-SS-A autoantibodies and a proteinuria of approximately 10 g/d.
Renal biopsy revealed a Class IV lupus glomerulonephritis and therefore a course of high-dose oral corticosteroids and cyclophosphamide was prescribed.
The rash responded well to the treatment.
Dr.Syrian's picture
by
طبيب مقيم

WoOoOoW ..
Thanx ..
We are studying such things this semester ..
a female in her second decade of life (usually between 2n and 3rd decades)
Quote:
This 18 year old SLE patient came to our Department due to a recent onset (3 months earlier) of malar rash and constitutional symptoms (weakness and malaise). The patient reported having a 5-year history of Raynaud's phenomenon (20% of patients) and arthralgia (90% of patients have Arthritis).
Abnormal results of laboratory studies included the presence of ANA (100%), anti-nDNA (=Anti-double-stranded DNA, It's specific, and found in 40-60%), anti-SS-A (30-50%) autoantibodies and a proteinuria of approximately 10 g/d.
Renal biopsy revealed a Class IV lupus glomerulonephritis (50% of patients have kidney involvement, Class IV Glomerulonephritis is the most common renal lesion 50% and most serious, and the most common cause of death in SLE is Renal Failure) and therefore a course of high-dose oral corticosteroids and cyclophosphamide was prescribed ((Immunosupressives)).
The rash responded well to the treatment.

Reference : ROBBINS Basic Pathology

thanx again Eye-wink ..

SAMO's picture
SAMO
السنة الخامسة


شكرا

qusei

Quote:
malar rash

also called butterfly rash and its painless non pruritic BUT photosensitive

so all the time adivse a SLE pt to not expose her/his face alot to sun

امرأة لا تتكرر's picture
امرأة لا تتكرر
السنة الخامسة
ابق على تواصل مع حكيم!
Google+