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تغيير تاريخ الادوية


تغيير تاريخ الادوية

احد الدكاترة االجهابذة في جامعة حلب يقول
1- الامبيسلين لايعطى عن طريق الفم لأن توافره الحيوي 40% Shocked
2- الاعطاء بالطريق الوريدي لا يتميز عن الاعطاء الفموي بشئ فسرعة التأثير والتوافر الحيوي نفسها
Shocked 3- لا يجوز اعطاء اي صاد عن طريق العضل بل يجب اعطاءه وريديا او فمويا Shocked
فما رأيكم يرحمكم الله Rolling Eyes Question Question Question

health is not adding years to life but adding life toyears
www.syriamg.com

life's picture
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Bioavailability of 40% is not bad! you can adjust by giving more medicine. especially with something cheap like the Penicillin the problem with something with less bioavailability like Vancomycin for example.
In many cases oral routs can be better than IV. for example, Metronidazole for C.diff colitis works better if given orally. Also if you are treating cholecystitis it may be better to give medicine orally because it come to the liver first.
remember that the oral rout is unreliable for hypotensive patients or those with nausea/ vomitting or gastroparesis.
Intramuscular injection is a really bad way to give any medicine. More often than not it is better to give the medicine orally than IM. However, keep in mind that this rout is used for outpatients who have to receive medicine that can't be given orally like Gentamicine
when giving IV by a pharmacist is not practical ( and should be illigal by the way

usymd

life wrote:
احد الدكاترة االجهابذة في جامعة حلب يقول
1- الامبيسلين لايعطى عن طريق الفم لأن توافره الحيوي 40% Shocked
2- الاعطاء بالطريق الوريدي لا يتميز عن الاعطاء الفموي بشئ فسرعة التأثير والتوافر الحيوي نفسها
Shocked 3- لا يجوز اعطاء اي صاد عن طريق العضل بل يجب اعطاءه وريديا او فمويا Shocked
فما رأيكم يرحمكم الله Rolling Eyes Question Question Question

It is really quite difficult to give absolute rules. For examples one IM injection of oily chlromphenicol is the treatment of choice for meningococcal meningitis during epidemics in the African meningitis belt (cheap and adequate as most cases are managed as outpatients). However, this treatment is not used in developed countries.
The bottom line with antibiotic therapy is that you have to consider several aspects:
-Host-related factors (clinical manifestation and anatomic localization)
-Pathogenic agent-related factors (most importantly antibiotic resistance)
-Environment-related factors (availability of the antibiotic, hospitalization/outpatient).

Frenchy
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