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Regenerative medicine for insulin deficiency: creation of pancreatic islets and bioartificial pancreas.


Regenerative medicine for insulin deficiency: creation of pancreatic islets and bioartificial pancreas.

Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan,

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Recent advances in pancreas organogenesis have greatly improved the understanding of cell lineage from inner cell mass to fully differentiated beta-cells.
Based upon such knowledge, insulin-producing cells similar to beta-cells to a certain extent have been generated from various cell sources including embryonic stem cells (ESCs) and induced pluripotent stem (iPS) cells, although fully differentiated cells comparable to beta-cells are not yet available.
The bioartificial pancreas is a therapeutic approach to enable allo- and xenotransplantation of islets without immune suppression.
Among several types of bioartificial pancreases (BAPs), micro-encapsulated porcine islets are already in use in clinical trials and may, perhaps, replace islet transplantation in the near future.
Some types of bioartificial pancreas such as macro-encapsulation are also useful for keeping transplanted cells enclosed in case retrieval is necessary. Therefore, early clinical applications of artificially generated beta-like cells, especially those from ESCs or iPS cells, will be considered in combination with retrievable BAPs.

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i just found it amazing ... that even though the normal beta islet transplantation is still under study they have started to study making artificial islet and bio artificial Pancreas
and sadly here we still find pancreas transplantation a great procedure

لك الحمد ربي ..

by


what is even more amazing is that when you write a subject in english on hakeem it would be read only 7 times in 1 hour ((4 of these 7 time you read it Laughing out loud ))

HMS

you can always ask me to translate it, but I don't do it for free! Twisted Evil

The study is good by the way Surprised

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Angel Anas
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thanx Phantom And Angel Anas Surprised...
Ok Next Time inshala im going to put a hot arabic heading .... it's really Crazy just 31 reading in 2 dayconfused
HMS


thank you any way.......

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MARSHAL
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