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Infant 'colic'
The term 'colic' is used to describe a common symptom complex which occurs during the first few months of life. Paroxysmal, inconsolable crying or screaming accompanied by drawing up of the knees takes place several times a day, particularly in the evening. There is no firm evidence that the cause is intestinal, but this is often suspected. The condition usually resolves by 4 months of age. Occasionally, cow's milk protein intolerance or gastro-oesophageal reflux may be responsible. Sympathetic advice is helpful. The condition is essentially benign, although it may precipitate non-accidental injury in infants already at risk. Therapies such as gripe water are of unproven benefit. In severe, persistent cases an empirical 2-week trial of a cow's milk-free diet followed by a trial of anti-reflux treatment may be worthwhile.