المظاهر السريرية لداء ويبل whipple disease

Whipple's disease is most likely caused by infection with Tropheryma whippelii. The disorder primarily affects middle-aged white men, and the onset of symptoms is usually slow. Without treatment, it may be fatal.
Treatment is usually by ceftriaxone given through a vein, followed by an antibiotic taken by mouth, such as trimethoprim -sulfamethoxazole

thanx doctor....

شكرا خالد....

بحياتي ما حأعرف شخص هيك مرض بهيك اعراض
على كل حال هو مرض نادر
بس إذا في هيك أعراض خرج نعمله فحص سريري ..

think of this disease in any pt with arthralgia and abdominal pain and diarrhea (and weight loss)
and hyperpegmintation as i remember...
and imagine: arthralgia is the most common manifestation...

how is it diagnosed??