المعلومة
Causes of Hematuria: TICS
T: trauma (e.g. foley catheter)
tumor (e.g. RCC)
toxins (e.g.drugs like cyclophosphamide)
I: Infection (e.g. cystitis)
Inflammatory process (e.g. Goodpasture's sy)
C: calculi
cysts
congenital anomalies
S: Surgery (e.g. prostatic resection)
Sickle cell disease
Somewhere else (e.g. menses)
T: trauma (e.g. foley catheter)
tumor (e.g. RCC)
toxins (e.g.drugs like cyclophosphamide)
I: Infection (e.g. cystitis)
Inflammatory process (e.g. Goodpasture's sy)
C: calculi
cysts
congenital anomalies
S: Surgery (e.g. prostatic resection)
Sickle cell disease
Somewhere else (e.g. menses)
المرجع
Ferri clinical advisor
Fri, 2008-03-28 14:24

Ghufran
بعد التخرج
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شكرا غفران وهي صورة حاطتها هبة :

تكلمت سابقا عن اسبابها :
Stricture
Stones
Infection
Inflammation
Infarction
Tumor
Trauma
Tb
thanx,
about cyclophosphamide:
it causes Hemorrhagic Cystitis
about cyclophosphamide:
it causes Hemorrhagic Cystitis
and TCC , too
as we know , the most common cancer of bladder is TCC
what is the risk factor for SCC of bladder ?
بلهارسيا
تدخين ..
وفي عالم بتتهم التريبتوفان كمان ..
and the reason of Hemorrhagic Cystitis is a one of the metabolites of cyclophosphamide which voids through the bladder
so we advice the patients who take it to void their bladder frequently and to drink a lot quantity of water
Thanks dr.moonberg
the measures u mentioned usually suffice 2 prvent Cyclophosphamide induced bladder toxicity. But also there's a drug that reacts with the urotoxic metabolites inorder 2 decrese their toxicity.
it's Mesna: some (not all) recommened it. also used with Ifosfamide for the same reason