LV diastolic pressure is determined by the volume of blood in the ventricle and the distensibility or compliance of the entire cardiovascular system. Cardiovascular compliance is determined principally by the LV, but is also influenced by the left atrium (LA), pulmonary vessels, right ventricle (RV), and systemic arteries.
Pulmonary function is also dependent upon LV diastolic properties. During diastole the LV, LA, and pulmonary veins form a "common chamber" which is continuous with the pulmonary capillary bed (show figure 1). Thus, an increase in LV diastolic pressure will increase pulmonary capillary pressure which can cause dyspnea, exercise limitation, and pulmonary congestion.