الجلدية

A 72-year-old man presents with large, tense, pruritic bullae on the lower abdomen, groin, and inner thighs. Skin biopsy reveals IgG antibodies with linear immunofluorescence at the epidermal basement membrane. To what cell junctions are the antibodies binding?

A. Adherens junctions
B. Desmosomes
C. Gap junctions
D. Hemidesmosomes
E. Tight junctions

A 7-year-old elementary school child presents with her mother to the clinic for evaluation of
itching. They deny any exposure to new soaps or detergents, pollens or grasses, or new foods.
On physical examination, there are small papules, pustules, lichenified areas, and excoriations.
Using a magnifying lens, you identify a burrow on the finger webs. What is the most likely
diagnosis?
(A) Scabies
(B) Atopic dermatitis
(C) Acne
(D) Telangiectasias