Acute Cutaneous Lupus Erythematosus

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Dr.Syrian - الإثنين, 2007-02-19 13:21 | الجلدية | الطب الداخلي › الرثوية | الصور الطبية › العلامات السريرية | المحتوى الطبي

This 18 year old SLE patient came to our Department due to a recent onset (3 months earlier) of malar rash and constitutional symptoms (weakness and malaise). The patient reported having a 5-year history of Raynaud's phenomenon and arthralgia.
Abnormal results of laboratory studies included the presence of ANA, anti-nDNA, anti-SS-A autoantibodies and a proteinuria of approximately 10 g/d.
Renal biopsy revealed a Class IV lupus glomerulonephritis and therefore a course of high-dose oral corticosteroids and cyclophosphamide was prescribed.
The rash responded well to the treatment.

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SAMO - الثلاثاء, 2007-10-30 01:31

WoOoOoW ..
Thanx ..
We are studying such things this semester ..
a female in her second decade of life (usually between 2n and 3rd decades)

اقتباس:

This 18 year old SLE patient came to our Department due to a recent onset (3 months earlier) of malar rash and constitutional symptoms (weakness and malaise). The patient reported having a 5-year history of Raynaud's phenomenon (20% of patients) and arthralgia (90% of patients have Arthritis).
Abnormal results of laboratory studies included the presence of ANA (100%), anti-nDNA (=Anti-double-stranded DNA, It's specific, and found in 40-60%), anti-SS-A (30-50%) autoantibodies and a proteinuria of approximately 10 g/d.
Renal biopsy revealed a Class IV lupus glomerulonephritis (50% of patients have kidney involvement, Class IV Glomerulonephritis is the most common renal lesion 50% and most serious, and the most common cause of death in SLE is Renal Failure) and therefore a course of high-dose oral corticosteroids and cyclophosphamide was prescribed ((Immunosupressives)).
The rash responded well to the treatment.

Reference : ROBBINS Basic Pathology

thanx again Eye-wink ..