مريضة تعاني من آلام منتشرة..A female pt complaining of aching all over

A 35-year-old woman complains of aching all over. She says she sleeps poorly and all her joints hurt. Symptoms have progressed over several years. Physical exam shows multiple points of tenderness over the neck, shoulders, elbows, and near her knees. There is no joint swelling or deformity. A complete blood count and erythrocyte sedimentation rate are normal. Rheumatoid factor is negative. There is no tenderness over the median third of the clavicle, the medial malleolus, or the forehead.
The best therapeutic option in this patient is:
a. Amitriptyline at night
b. Prednisone
c. Aspirin and methotrexate
d. Plaquenil