What is BNP ?

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المعلومة

B-type natriuretic peptide (BNP): A 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes (heart muscles cells) in the ventricles.
The levels of B-type natriuretic peptide (BNP) are elevated in patients with left ventricular dysfunction. BNP levels correlate with both the severity of symptoms and the prognosis in congestive heart failure.

BNP levels are higher in patients with dyspnea (shortness of breath) due to heart failure than in patients with dyspnea from other causes. Rapid measurement of BNP in the emergency department therefore helps in the evaluation and treatment of patients with acute dyspnea and reduces the time to discharge and the cost of their treatment.

BNP appears to be a useful marker of cardiovascular risk, even in people with no clinical evidence of cardiovascular disease. The levels of BNP predict the risk of heart failure, first cardiovascular events, atrial fibrillation, and stroke or transient ischemic attack.

المرجع



In Oxford Handbook of Clinical Medicine : If ECG and BNP are normal,heart failure is unlikely, and an ulternative diagnosis should be considered.



and my Q is : is this test applied in Syria?
I have never heard about it !!!



there is BNP (Brain Natriutic Peptide)
and ANP (Atrial natriutic Peptide)
see that
BNP is a 32-amino acid polypeptide containing a 17-amino acid ring structure common to all natriuretic peptides. Unlike ANP, whose major storage sites are in both the atria and ventricles, the major source of plasma BNP is the cardiac ventricles, suggesting that BNP may be a more sensitive and specific indicator of ventricular disorders than other natriuretic peptides. The release of BNP appears to be in direct proportion to ventricular volume expansion and pressure overload. BNP is an independent predictor of high LV end-diastolic pressure and is more useful than ANP or NE levels for assessing mortality risk in patients with CHF.
and i think that ANP exsistes in Syria
and BNP exsistes too cos it is simple and important

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