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Anorexia and Amenorrhea



صورة Rasha

السنة السادسة
المشاركات: 90

Hi
Can anybody tell me please how would anorexia cause amenorrhea ,I think it's through the hypothlamic tract but Anybody knows the exact meechanism or pathophysiology for it
Thank you

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somebody
Rasha - الأحد, 2008-04-27 21:24عودة للأعلى
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فريق دليل اختيار الاختصاصالقسم العلمي
حكيم فعّال


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HYpogonadotrophic Hypogonadism
that is all I know
الأحد, 2008-04-27 21:34عودة للأعلى
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صورة summayah

السنة السادسة
المشاركات: 38

Amenorrhea is one of the cardinal features of anorexia nervosa and is associated with hypothalamic dysfunction. Earlier theories of weight loss, decreased body fat, or exercise do not fully explain the etiology of amenorrhea in anorexia nervosa. Disturbances in central dopaminergic and opioid activity have been described in anorexia nervosa and both these substances are known to modulate gonadotropin-releasing hormone (GnRH)-mediated luteinizing hormone (LH) release. Serum LH, folliclestimulating hormone (FSH), estradiol, and prolactin levels were measured at baseline and after administration of metoclopramide (a central D-2 dopamine receptor blocker) in 10 newly diagnosed women with anorexia nervosa and in 10 healthy age-matched controls. Basal prolactin levels and the prolactin response to metoclopramide were significantly impaired in the group with anorexia nervosa. Metoclopramide did not induce a significant rise in LH levels in either the anorexic or the control groups. Neurotransmitter abnormalities may influence hypothalamic dysfunction in anorexia nervosa but the exact mechanism remains to be determined
http://www3.interscience.wiley.com/journal/112413520/abstract?CRETRY=1&SRETRY=0
الأحد, 2008-10-12 21:06عودة للأعلى
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حكيم فعّال

صورة dr.tabban

بعد التخرج
المشاركات: 2849

so nothing is for sure !

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be the change you want to see in the world
الأحد, 2008-10-12 21:37عودة للأعلى
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