Introduction to Skin Infections:microbiology


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Introduction to Skin Infections:
The skin is comprised of the epidermis, dermis and subcutaneous layers, separated from the underlying muscle by the fascia.Each layer has different characteristics and a different spectrum of infections. The keratinized layer can be infected by lice, papilloma virus and some fungi. Of the bacterial diseases that infect the skin, impetigo is the most superficial, followed (as one goes deeper into the skin) by erysipelas, cellulitis and fasciitis. A kind of fasciitis called necrotizing fasciitis is often called a flesh-eating infection due to the ability of the causative bacteria to quickly move along the plane of the fascia and cause widespread necrosis. Folliculitis, an infection of the hair follicle, can be quite superficial or form a deeper abscess. Any of the infections except the very superficial can, by toxigenic mechanisms or direct spreading, progress to shock and even death. By far the commonest bacteria causing infections of the skin are Staphylococcus aureus and Streptococcus pyogenes. These can lead to the very serious conditions, toxic shock and toxic shock-like syndrome, but even in the absence of these complications can be very painful and cause widespread damage. Haemophilus influenzae may cause erysipelas or cellulitis, particularly in children, whereas burn infections are most frequently caused by Staphylococcus and Pseudomonas. The enteric bacteria, which have the ability to cause gram negative sepsis, can also be a problem any time there is large scale damage to the skin. The spore-forming anaerobes, the Clostridia, also can cause very dangerous infections including myonecrosis or gas gangrene as well as tetanus that begin by skin penetration. Traumatic infections caused by animal bites or scratches have a unique set of causative agents with rabies being the most feared.

now asnswer the following questions after u read that info:

Question 1 - Single Best Answer:

Most skin infections are?

A) contracted from animals
B) spread by the respiratory route
C) contracted from doctors and nurses
D) endogenous infections contracted from bacteria colonizing the skin and nasopharynx

Question 2 - Single Best Answer:

What is the causative agent of impetigo?

A) Staphylococcus aureus
B) Staphylococcus epidermidis
C) Streptococcus pyogenes
D) E.coli
E) more than one of the above

Question 3 - Single Best Answer:

Which of the following is a predisposing factor for infection of the deeper layers of the skin?

A) trauma
B) surgery
C) diabetes
D) alcoholism
E) all of the above

Question 4 - Single Best Answer:

A patient has progressive warmth, redness, swelling, and tenderness of an extremity, but only appears mildly ill. He or she likely has?

A) impetigo
B) cellulitis
C) abscess
D) gas gangrene
E) toxic shock

Question 5 - Single Best Answer

Features that distinguish necrotizing fasciitis from cellulitis include?

A) redness and swelling
B) elevated WBC
C) severe pain in the absence of cutaneous findings
D) crusty vesicles
E) fever

to be continued.....

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


فريق دليل اختيار الاختصاصالقسم العلمي
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صورة mbs2380

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Arrow

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


حكيم فعّال

صورة Vince Carter

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الله يعطيك العافية عالجهود الجبارة... Laughing out loud Laughing out loud Laughing out loud

Q1 is B) (not sure about this...
Q2: I think it is staphylococcus aureus
Q3 is A) trauma
Q4 is E) toxic shock
Q5 is A) redness and swelling

هادا يلي طلع معي.... ان شاء الله يكون صح....
و بعدين أنا يلي (آت يور كوماندز)Embarrased Embarrased Embarrased

waiting for your answers brother
.....

___________


الأخوة رابطة رائعة يصعب كسرها!!


فريق دليل اختيار الاختصاصالقسم العلمي
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اقتباس:
Q1 is B) (not sure about this...
Q2: I think it is staphylococcus aureus
Q3 is A) trauma
Q4 is E) toxic shock
Q5 is A) redness and swelling

thank u for participation brother Khaled..
what I wrote in green is the q and its answer

Most skin infections are?

A) contracted from animals:somecomes from bites of animals but not most of them..
B) spread by the respiratory route:Noneare spread through the respiratory route...
C) contracted from doctors and nurses:some,indeed but not most..
D) endogenous infections contracted from bacteria colonizing the skin and nasopharynx:Staphylococcus aureus is carried by many individuals in the anterior nares and also on the skin and Streptococcus often colonizes the pharynx and the skin. So most skin infections are caused by an individual's own flora. Not all, of course.


question2:
What is the causative agent of impetigo?

A) Staphylococcus aureus:yes it is one of them but not the best answer...
B) Staphylococcus epidermidis:this usually lives in skin with no problems...
C) Streptococcus pyogenes:yes it is one of them but not the best answer...
D) E.coli:that does not cause impetigo..
E) more than one of the above:yes, either Staphylococcus aureus, Streptococcus pyogenes (the most common) or a mixture of the two can cause impetigo

Question3":
Which of the following is a predisposing factor for infection of the deeper layers of the skin?

A) trauma
B) surgery
C) diabetes:this is definitely one, but there is a better answer. Diabetes can compromise both the nerves and the small blood vessels, leading to inadvertent injuries and poor wound healing.
D) alcoholism:this is definitely one, but there is a better answer. This is likely a predisposing factor due to inadvertent injury
E) all of the above:yes, anything that causes a break in the skin and/or compromises the blood flow to the skin will predispose to skin infections


A patient has progressive warmth, redness, swelling, and tenderness of an extremity, but only appears mildly ill. He or she likely has?

A) impetigo:no, this presents with pustules or vesicles that can open and crust over

B) cellulitis:yes, a key here is the progressive nature of the disease
C) abscess:no, an abscess is a confined infection
D) gas gangrene:no, this presents with symptoms of necrotizing fasciitis; severe pain, bullous lesions, purplish skin, evidence of gas in tissues, and crepitance
E) toxic shock:well, actually the patient could develop toxic shock or toxic shock-like syndrome if he/she were infected with Staphylococcus aureus or Streptococcus pyogenes, respectively. But not all strains of Staph or Strep can lead to this complication. They must carry the gene for the toxin.


question5:
Features that distinguish necrotizing fasciitis from cellulitis include?

A) redness and swelling:no, this can be found in both necrotizing fasciitis and cellulitis
B) elevated WBC:no, this is found in both necrotizing fasciitis and cellulitis, although the count may be higher in necrotizing fasciitis .
C) severe pain in the absence of cutaneous findings:yes, this can be a sign of necrotizing fasciitis.another is bullous skin lesions and dark reddish-purple skin
D) crusty vesicles:no, these are characteristic of impetigo, a very superficial infection
E) fever:no, this is found in both necrotizing fasciitis and cellulitis, although the fever could be higher in the case of necrotizing fasciitis

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


حكيم فعّال

صورة Vince Carter

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oooooooooppppppppppppssssssss
none of my answers were right.....Embarrased Embarrased Embarrased
i tried my best brother....
شكرا عالفائدة......

___________


الأخوة رابطة رائعة يصعب كسرها!!


فريق دليل اختيار الاختصاصالقسم العلمي
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صورة mbs2380

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GAS gangrene:

Impetigo:

Cellulitis:

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


فريق دليل اختيار الاختصاصالقسم العلمي
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Actually I also hadn't known most of them until I saw the answers...I mean it is very normal to make mistakes here but not to make them infront of the patient..the most important is the benefit

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


فريق دليل اختيار الاختصاصالقسم العلمي
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here are the others :

Question 6 - Single Best Answer

Antibiotic ointment applied to the anterior nares is used for which of the following?

A) clear carriage of Staphylococcus aureus
B) impetigo
C) facial cellulitis caused by Haemophilus influenzae
D) sinus infection
E) clenched fist injury

Question 7 - Single Best Answer

A skin abscess or boil is most often caused by?

A) Staphylococcus aureus
B) Staphylococcus epidermidis
C) Streptococcus pyogenes
D) Pseudomonas aeruginosa
E) Clostridium tetani

Question 8 - Single Best Answer

Clostridium tetani is extremely dangerous because?

A) it can grow in the absence of air
B) it can cause gangrene
C) it produces a neurotoxin
D) it is resistant to antibiotics
E) it is a spore forming organism

Question 9 - Single Best Answer

Infections of dog and cat bites are likely to be caused by?

A) Staphylococcus aureus
B) Staphylococcus epidermidis
C) Streptococcus pyogenes
D) Eikenella corrodons
E) Pasteurella sp

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


حكيم فعّال

صورة Vince Carter

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you are totally right......
the most important is the benefit....and that is why i answered without being sure about my answers....

___________


الأخوة رابطة رائعة يصعب كسرها!!


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صورة qusei


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8-c
9-e
6-b
7-a

___________

حسبي من سؤالي علمك بحالي


فريق دليل اختيار الاختصاصالقسم العلمي
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صورة mbs2380

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اقتباس:
8-c
9-e
6-b
7-a

So dear Qusei u've got 3 out of 4 ...excellent
Q AND THEIR ANSWERS IN GREEN

Question 6 - Single Best Answer

Antibiotic ointment applied to the anterior nares is used for which of the following?

A) clear carriage of Staphylococcus aureus:yes, this is very important in a hospital setting where personnel can spread Staph infections, and also in individuals with recurring Staph folliculitis or abscesses
B) impetigo:it wouldn't help this much
C) facial cellulitis caused by Haemophilus influenzae:no, this would require systemic antibiotics
D) sinus infection:no, topical antibiotics in the nose wouldn't help this
E) clenched fist injury:this usually occurs when someone punches someone else in the mouth. Teeth cause injury to the fist of the puncher and the wound gets contaminated with saliva (puncheeÕs revenge?). As with human bites, the most common causative organism is Eikenella corrodens. Nasally applied antibiotics would not help, they would have to be applied to the site of the injury.

---------------------

Question 7 - Single Best Answer:
A skin abscess or boil is most often caused by?

A) Staphylococcus aureus:Yes. Some people think that the coagulase helps to cause to the formation of an abscess
B) Staphylococcus epidermidis:this doesnÕt cause abscesses. It does not make coagulase which is one reason that some people think that coagulase contributes to the pathogenesis of an abscess
C) Streptococcus pyogenes:This is more likely to cause spreading infections, rather than "walled off" infections
D) Pseudomonas aeruginosa:This doesnÕt cause abscesses. In an abscess there may be a low oxygen tension as the blood supply has been cut off. Pseudomonas aeruginosa is a strict aerobe with no fermentative metabolism, so wouldn"t grow well in an abscess
E) Clostridium tetani:no, often this causes no signs of infecting the skin at all

_________________________________

Question 8 - Single Best Answer:
Clostridium tetani is extremely dangerous because?

A) it can grow in the absence of air:it can, but this is not what makes it dangerous
B) it can cause gangrene:no, that is a different Clostridium>
C) it produces a neurotoxin:yes, the toxin causes inhibition of release of an inhibitory neurotransmitter, resulting in tetanic spasms (contraction of opposing muscles at the same time). This is usually prevented by inhibitory interneurons in the spinal chord.

D) it is resistant to antibiotics:no, antibiotics can kill the organism but if the toxin is already in the system, the antibiotics don't help much
E) it is a spore forming organism:it is, but this is not what makes it so dangerous. The fact that it can form spores does figure in the pathogenesis of tetanus, however.

____________________________

Question 9 - Single Best Answer

Infections of dog and cat bites are likely to be caused by?

A) Staphylococcus aureus
B) Staphylococcus epidermidis
C) Streptococcus pyogenes
D) Eikenella corrodons:This causes infections of human bites (more common than you would think Laughing out loud !) but not animal bites
E) Pasteurella sp:yes, Pasteurella multocida is especially common in cat bites.

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


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صورة mbs2380

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اقتباس:
mbs2380 said:
I will start the next part soon.....

bassam says:ha ha ha!!! ..As if someone cares or give a damn .........

___________

All that you've taken from others Will be taken from you All that your dissonance smothers Will then come back to you Whatever happens tomorrow, and whatever you do Just keep in mind that the source and end is you


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صورة moonberg

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thanx
really valuable

___________

Whether you think you can or think you can't, either way you are right


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معلومات قيمة جدا............
وين طلاب الثالثة الباقيين Eye-wink

___________

حسبي من سؤالي علمك بحالي


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صورة Vince Carter

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اقتباس:
معلومات قيمة جدا............
وين طلاب الثالثة الباقيين

Laughing out loud Laughing out loud Laughing out loud Laughing out loud

___________


الأخوة رابطة رائعة يصعب كسرها!!


فريق دليل اختيار الاختصاصالقسم العلمي
حكيم فعّال

صورة qusei


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هلأ خالد انت شاركت بس وين رفقاتك الباقيين Laughing out loud Laughing out loud

___________

حسبي من سؤالي علمك بحالي


حكيم فعّال

صورة Vince Carter

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بالفعل معلومات قيمة جدا
مشكور عمي بسام.....

اقتباس:

bassam says:ha ha ha!!! ..As if someone cares or give a damn .........

له لك بسام.......
وحياتك نحنا وراك متل حدالسيف...
أنت بس حط الأسئلة ....و نحنا منجاوب....
و يا جبل ما يهزك ريح.....

___________


الأخوة رابطة رائعة يصعب كسرها!!